New Insights into Osteoarthritis Treatment Development Published in NatureReviews Rheumatology
In a breakthrough publication, Dr. Ali Mobasheri (ENCANTO project partner from University of Oulu) and Dr. Richard Loeser present a novel approach to osteoarthritis (OA) treatment in the latest issue of Nature Reviews Rheumatology (May 2024). Their paper, titled “Clinical phenotypes, molecular endotypes and theratypes in OA therapeutic development,” proposes a shift from the traditional one-size-fits-all model of OA therapy towards a more personalized approach. By identifying distinct clinical phenotypes and molecular endotypes, the authors highlight the potential for “theratypes,” or tailored treatment strategies, that target specific biological mechanisms within OA subtypes. This paradigm shift could transform the landscape of OA treatment, potentially improving patient outcomes and paving the way for individualized therapies.
Publication link: Clinical phenotypes, molecular endotypes and theratypes in OA therapeutic development | Nature Reviews Rheumatology